| Ident. | Authors (with country if any) | Title |
|---|
| 000B40 (2016) |
Stephanie J. Munger [États-Unis] ; Xin Geng [États-Unis] ; R. Sathish Srinivasan [États-Unis] ; Marlys H. Witte [États-Unis] ; David L. Paul [États-Unis] ; Alexander M. Simon [États-Unis] | Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice |
| 000E08 (2016) |
Boksik Cha [États-Unis] ; Xin Geng [États-Unis] ; Md. Riaj Mahamud [États-Unis] ; Jianxin Fu [États-Unis] ; Anish Mukherjee [États-Unis] ; Yeunhee Kim [États-Unis] ; Eek-Hoon Jho [Corée du Sud] ; Tae Hoon Kim [États-Unis] ; Mark L. Kahn [États-Unis] ; Lijun Xia [États-Unis] ; J. Brandon Dixon [États-Unis] ; Hong Chen [États-Unis] ; R. Sathish Srinivasan [États-Unis] | Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves |
| 000E72 (2016) |
Pauliina Hartiala [Finlande] ; Anne M. Saarikko [Finlande] | Lymphangiogenesis and Lymphangiogenic Growth Factors. |
| 001590 (2015) |
Seydou Bakayoko [Mali] ; Nouhoum Guirou [Mali] | [Distichiasis: an anomaly of eyelashes]. |
| 001D52 (2015) |
Jan Kazenwadel [Australie] ; Kelly L. Betterman [Australie] ; Chan-Eng Chong [Australie] ; Philippa H. Stokes [Australie] ; Young K. Lee [Australie] ; Genevieve A. Secker [Australie] ; Yan Agalarov [Suisse] ; Cansaran Saygili Demir [Suisse] ; David M. Lawrence [Australie] ; Drew L. Sutton [Australie] ; Sebastien P. Tabruyn [Australie] ; Naoyuki Miura [Japon] ; Marjo Salminen [Finlande] ; Tatiana V. Petrova [Suisse] ; Jacqueline M. Matthews [Australie] ; Christopher N. Hahn [Australie] ; Hamish S. Scott [Australie] ; Natasha L. Harvey [Australie] | GATA2 is required for lymphatic vessel valve development and maintenance |
| 001D96 (2015) |
Amélie Sabine [Suisse] ; Esther Bovay [Suisse] ; Cansaran Saygili Demir [Suisse] ; Wataru Kimura [Japon] ; Muriel Jaquet [Suisse] ; Yan Agalarov [Suisse] ; Nadine Zangger [Suisse] ; Joshua P. Scallan [États-Unis] ; Werner Graber [Suisse] ; Elgin Gulpinar [États-Unis] ; Brenda R. Kwak [Suisse] ; Taija M Kinen [Suède] ; Inés Martinez-Corral [Espagne] ; Sagrario Ortega [Espagne] ; Mauro Delorenzi [Suisse] ; Friedemann Kiefer [Allemagne] ; Michael J. Davis [États-Unis] ; Valentin Djonov [Suisse] ; Naoyuki Miura [Japon] ; Tatiana V. Petrova [Suisse] | FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature |
| 001D97 (2015) |
Yasmeen Sheik [Inde] ; Sameera Fatima Qureshi [Inde] ; Basheeruddin Mohhammed [Inde] ; Pratibha Nallari [Inde] | FOXC2 and FLT4 Gene Variants in Lymphatic Filariasis. |
| 001F95 (2015) |
John D. Kanady [États-Unis] ; Stephanie J. Munger [États-Unis] ; Marlys H. Witte [États-Unis] ; Alexander M. Simon [États-Unis] | Combining Foxc2 and Connexin37 deletions in mice leads to severe defects in lymphatic vascular growth and remodeling |
| 002037 (2015) |
Johanna Liebl [Allemagne] ; Siwei Zhang [Allemagne] ; Markus Moser [Allemagne] ; Yan Agalarov [Suisse] ; Cansaran Saygili Demir [Suisse] ; Bianca Hager [Allemagne] ; James A. Bibb [États-Unis] ; Ralf H. Adams [Allemagne] ; Friedemann Kiefer [Allemagne] ; Naoyuki Miura [Japon] ; Tatiana V. Petrova [Suisse] ; Angelika M. Vollmar [Allemagne] ; Stefan Zahler [Allemagne] | Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. |
| 002038 (2015) |
Johanna Liebl [Allemagne] | Cdk5 and Foxc2 – a new relationship in the lymphatic vasculature |
| 002382 (2014) |
Ying Yang [États-Unis] ; Guillermo Oliver | Transcriptional control of lymphatic endothelial cell type specification. |
| 002972 (2014) |
Amélie Sabine [Suisse] ; Tatiana V. Petrova | Interplay of mechanotransduction, FOXC2, connexins, and calcineurin signaling in lymphatic valve formation. |
| 002E64 (2014) |
Carole Sargent [Royaume-Uni] ; Julien Bauer [Royaume-Uni] ; Muhamed Khalil [États-Unis] ; Parker Filmore [États-Unis] ; Michael Bernas [États-Unis] ; Marlys Witte [États-Unis] ; M. Peggy Pearson [États-Unis] ; Robert P. Erickson [États-Unis] | A Five Generation Family with a Novel Mutation in FOXC2 and Lymphedema Worsening to Hydrops in the Youngest Generation |
| 002E70 (2014) |
L-L Zhu [République populaire de Chine] ; Y-N Lv ; H-D Chen ; X-H Gao | A Chinese pedigree of lymphoedema-distichiasis syndrome with a novel mutation in the FOXC2 gene. |
| 002F37 (2013) |
M. Marc [France] ; M. Barreau ; M. Gerard ; L. Verneuil ; L. Derieux ; A. Dompmartin | [Lymphoedema distichiasis]. |
| 003300 (2013) |
Konstantin I. Ivanov ; Yan Agalarov ; Leena Valmu ; Olga Samuilova ; Johanna Liebl ; Nawal Houhou ; Hélène Maby-El Hajjami ; Camilla Norrmén ; Muriel Jaquet ; Naoyuki Miura ; Nadine Zangger ; Seppo Yl Herttuala ; Mauro Delorenzi ; Tatiana V. Petrova | Phosphorylation Regulates FOXC2-Mediated Transcription in Lymphatic Endothelial Cells |
| 003983 (2013) |
Yoji Ogura [Japon] ; Shoji Yabuki [Japon] ; Aritoshi Iida [Japon] ; Ikuyo Kou [Japon] ; Masahiro Nakajima [Japon] ; Hiroki Kano [Japon] ; Masaaki Shiina [Japon] ; Shinichi Kikuchi [Japon] ; Yoshiaki Toyama [Japon] ; Kazuhiro Ogata [Japon] ; Masaya Nakamura [Japon] ; Morio Matsumoto [Japon] ; Shiro Ikegawa [Japon] | FOXC2 Mutations in Familial and Sporadic Spinal Extradural Arachnoid Cyst |
| 003D03 (2012) |
M. Blein [France] ; L. Martin ; G. Lorette ; L. Vaillant ; F. Baulieu ; A. Maruani | [Primary lymphoedema in children]. |
| 004075 (2012) |
Edyta Sutkowska [Pologne] ; Justyna Gil ; Agnieszka Stembalska ; Aneta Hill-Bator ; Andrzej Szuba | Novel mutation in the FOXC2 gene in three generations of a family with lymphoedema-distichiasis syndrome. |
| 004135 (2012) |
R P Erickson | Massively parallel DNA sequencing and the new approach to mutation detection: a step towards a lymphedema fine panel. |
| 004257 (2012) |
Gwendolyn De Bruyn [Belgique] ; Alexandra Casaer ; Katrien Devolder ; Geert Van Acker ; Hilde Logghe ; Koen Devriendt ; Luc Cornette | Hydrops fetalis and pulmonary lymphangiectasia due to FOXC2 mutation: an autosomal dominant hereditary lymphedema syndrome with variable expression. |
| 004282 (2012) |
Chen-Hsiang Yeang [Taïwan] ; Gwo-Chin Ma [Taïwan] ; Jin-Chung Shih [Taïwan] ; Yu-Shih Yang [Taïwan] ; Chih-Ping Chen [Taïwan] ; Shun-Ping Chang [Taïwan] ; Sheng-Hai Wu [Taïwan] ; Chin-San Liu [Taïwan] ; Shou-Jen Kuo [Taïwan] ; Hung-Chieh Chou [Taïwan] ; Wuh-Liang Hwu [Taïwan] ; Alan D. Cameron [Royaume-Uni] ; Norman A. Ginsberg [États-Unis] ; Yi-Shing Lin [Taïwan] ; Ming Chen [Taïwan] | Genome-Wide Gene Expression Analysis Implicates the Immune Response and Lymphangiogenesis in the Pathogenesis of Fetal Chylothorax |
| 004443 (2012) |
S. Michelini [Italie] ; D. Degiorgio ; M. Cestari ; D. Corda ; M. Ricci ; M. Cardone ; A. Mander ; L. Famoso ; E. Contini ; R. Serrani ; L. Pinelli ; S. Cecchin ; M. Bertelli | Clinical and genetic study of 46 Italian patients with primary lymphedema. |
| 004731 (2012) |
Matthew G. Butler [États-Unis] ; Susan L. Dagenais [États-Unis] ; José L. Garcia-Perez [États-Unis, Espagne] ; Pascal Brouillard [Belgique] ; Miikka Vikkula [Belgique] ; Peter Strouse [États-Unis] ; Jeffrey W. Innis [États-Unis] ; Thomas W. Glover [États-Unis] | Microcephaly, intellectual impairment, bilateral vesicoureteral reflux, distichiasis, and glomuvenous malformations associated with a 16q24.3 contiguous gene deletion and a Glomulin mutation |
| 004C98 (2011) |
Russell H. Mellor [Royaume-Uni] ; Naomi Tate ; Anthony W B. Stanton ; Charlotte Hubert ; Taija M Kinen ; Alberto Smith ; Kevin G. Burnand ; Steve Jeffery ; J Rodney Levick ; Peter S. Mortimer | Mutations in FOXC2 in humans (lymphoedema distichiasis syndrome) cause lymphatic dysfunction on dependency. |
| 004F38 (2011) |
Hiroshi Shimoda [États-Unis] ; Michael J. Bernas ; Marlys H. Witte | Dysmorphogenesis of lymph nodes in Foxc2 haploinsufficient mice. |
| 004F82 (2011) |
John D. Kanady [États-Unis] ; Michael T. Dellinger [États-Unis] ; Stephanie J. Munger [États-Unis] ; Marlys H. Witte [États-Unis] ; Alexander M. Simon [États-Unis] | Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax |
| 005492 (2010) |
Loïc Vaillant [France] ; Valérie Tauveron | [Primary lymphedema of limbs]. |
| 005606 (2010) |
Rocío Sánchez-Carpintero [Espagne] ; Pablo Dominguez ; María Teresa Nú Ez ; Ana Pati O-García | Spinal extradural arachnoid cysts in lymphedema-distichiasis syndrome. |
| 005682 (2010) |
M. Todd [Royaume-Uni] ; J. Welsh ; M W Drummond | Primary lymphedema and acute leukemia--is there a link? |
| 005A56 (2010) |
A-L Fauret [France] ; E. Tuleja ; X. Jeunemaitre ; S. Vignes | A novel missense mutation and two microrearrangements in the FOXC2 gene of three families with lymphedema-distichiasis syndrome. |
| 005A67 (2010) |
Antonella Fabretto [Italie] ; Alison Shardlow ; Flavio Faletra ; Loredana Lepore ; Uros Hladnik ; Paolo Gasparini | A case of lymphedema-distichiasis syndrome carrying a new de novo frameshift FOXC2 mutation. |
| 005B38 (2010) |
Pranoot Tanpaiboon [Thaïlande] ; Piranit Kantaputra [Thaïlande] ; Karn Wejathikul [Thaïlande] ; Wirawit Piyamongkol [Thaïlande] | c. 595‐596 insC of FOXC2 underlies lymphedema, distichiasis, ptosis, ankyloglossia, and Robin sequence in a Thai patient |
| 006020 (2009) |
Arash Ghalamkarpour [Belgique] ; Christian Debauche ; Eric Haan ; Nicole Van Regemorter ; Yves Sznajer ; Dominique Thomas ; Nicole Revencu ; Yves Gillerot ; Laurence M. Boon ; Miikka Vikkula | Sporadic in utero generalized edema caused by mutations in the lymphangiogenic genes VEGFR3 and FOXC2. |
| 006182 (2009) |
M H Witte [États-Unis] ; R P Erickson ; M. Khalil ; M. Dellinger ; M. Bernas ; T. Grogan ; H. Nitta ; J. Feng ; D. Duggan ; C L Witte | Lymphedema-distichiasis syndrome without FOXC2 mutation: evidence for chromosome 16 duplication upstream of FOXC2. |
| 006288 (2009) |
Jie Huang [États-Unis] ; Lisa K. Dattilo [États-Unis] ; Ramya Rajagopal [États-Unis] ; Ying Liu [États-Unis] ; Vesa Kaartinen [États-Unis] ; Yuji Mishina [États-Unis] ; Chu-Xia Deng [États-Unis] ; Lieve Umans [Belgique] ; An Zwijsen [Belgique] ; Anita B. Roberts [États-Unis] ; David C. Beebe [États-Unis] | FGF-regulated BMP signaling is required for eyelid closure and to specify
conjunctival epithelial cell fate |
| 006586 (2009) |
M. A. M. Van Steensel [Pays-Bas] ; R. J. Damstra [Pays-Bas] ; M. Heitink [Pays-Bas] ; R. S. Bladergroen [Pays-Bas] ; J. Veraart [Pays-Bas] ; Peter M. Steijlen [Pays-Bas] ; M. Van Geel [Pays-Bas] | Novel missense mutations in the FOXC2 gene alter transcriptional activity |
| 006885 (2008) |
K. Rutscher [Allemagne] ; J. Wilting | Transcription factor FOXC2 demarcates the jugular lymphangiogenic region in avian embryos. |
| 006A01 (2008) |
M T Dellinger [États-Unis] ; K. Thome ; M J Bernas ; R P Erickson ; M H Witte | Novel FOXC2 missense mutation identified in patient with lymphedema-distichiasis syndrome and review. |
| 006B68 (2008) |
Sajid Malik [Allemagne] ; Karl-Heinz Grzeschik | Congenital, low penetrance lymphedema of lower limbs maps to chromosome 6q16.2-q22.1 in an inbred Pakistani family. |
| 006D53 (2008) |
Robert E. Ferrell [États-Unis] ; David N. Finegold [États-Unis] | Research Perspectives in Inherited Lymphatic Disease |
| 006D71 (2008) |
Glen Brice [Royaume-Uni] | Perinatal diagnosis of a lymphoedema‐distichiasis syndrome |
| 006E09 (2008) |
Maaike Vreeburg ; Martijn V. Heitink ; Robert J. Damstra [Allemagne] ; Ute Moog [Allemagne] ; Michel Van Geel [Allemagne] ; Maurice A. M. Van Steensel [Allemagne] | Lymphedema–distichiasis syndrome: a distinct type of primary lymphedema caused by mutations in the FOXC2 gene |
| 006F80 (2008) |
Tayebeh Rezaie [États-Unis] ; Rose Ghoroghchian [États-Unis] ; Rachel Bell [Royaume-Uni] ; Glen Brice [Royaume-Uni] ; Ali Hasan [Royaume-Uni] ; Kevin Burnand [Royaume-Uni] ; Steve Vernon [Royaume-Uni] ; Sahar Mansour [Royaume-Uni] ; Peter Mortimer (dermatologue) [Royaume-Uni] ; Steve Jeffery [Royaume-Uni] ; Anne Child [Royaume-Uni] ; Mansoor Sarfarazi [États-Unis] | Primary non-syndromic lymphoedema (Meige disease) is not caused by mutations in FOXC2 |
| 007183 (2007) |
Russell H. Mellor [Royaume-Uni] ; Glen Brice ; Anthony W B. Stanton ; Jane French ; Alberto Smith ; Steve Jeffery ; J Rodney Levick ; Kevin G. Burnand ; Peter S. Mortimer | Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb. |
| 007273 (2007) |
Amy E. Young [États-Unis] ; Leslie P. Bower ; Verena K. Affolter ; Hilde E V. De Cock ; Gregory L. Ferraro ; Danika L. Bannasch | Evaluation of FOXC2 as a candidate gene for chronic progressive lymphedema in draft horses. |
| 007571 (2007) |
M. A. M. Van Steensel [Pays-Bas] ; M. Van Geel [Pays-Bas] ; C. Schrander-Stumpel [Pays-Bas] ; P. M. Steijlen [Pays-Bas] ; J. C. J. M. Veraart [Pays-Bas] | Lymphedema, cardiac septal defects, and characteristic facies: Possible new case of Irons–Bianchi syndrome |
| 007686 (2007) |
S. Kumar [Arabie saoudite] ; C. Carver ; S. Mccall ; G. Brice ; P. Ostergaard ; Peter Mortimer (dermatologue) [Royaume-Uni] ; S. Jeffery [Royaume-Uni] | A family with lymphoedema‐distichiasis where identical twins have a discordant phenotype |
| 007864 (2006) |
Subash Babu [États-Unis] ; Carla P. Blauvelt ; V. Kumaraswami ; Thomas B. Nutman | Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence. |
| 007A17 (2006) |
A. Noon [États-Unis] ; R J Hunter ; M H Witte ; B. Kriederman ; M. Bernas ; M. Rennels ; D. Percy ; S. Enerb Ck ; R P Erickson | Comparative lymphatic, ocular, and metabolic phenotypes of Foxc2 haploinsufficient and aP2-FOXC2 transgenic mice. |
| 007E46 (2005) |
Subash Babu ; V. Kumaraswami ; Thomas B. Nutman | Transcriptional Control of Impaired Th1 Responses in Patent Lymphatic Filariasis by T-Box Expressed in T Cells and Suppressor of Cytokine Signaling Genes |
